Evidence for a Possible Genetic Influence on Noise‐Induced Cochlear Damage

Evidence for a Strong Genetic Influence on Carotid Plaque Characteristics

Genetic models for the natural history of smoking: evidence for a genetic influence on smoking persistence.

We reanalyze data from the 1981 mailed questionnaire survey of the Australian twin register, to test for a genetic effect on smoking persistence (whether or not a smoker quits smoking). In the young cohort, aged 18-30 years, there are too few ex-smokers to permit resolution of genetic and non-genetic models. In the older cohort, we find a significant and substantial genetic effect on smoking pe...

Trichloroethylene ototoxicity: evidence for a cochlear origin.

Trichloroethylene (TCE) is known to produce an unusual pattern of hearing impairment in laboratory animals marked by a preferential loss of threshold sensitivity at midfrequencies. The purpose of this research was to determine whether the TCE-induced auditory deficit results from cochlear dysfunction. Adult Long Evans hooded rats were exposed via inhalation to either 0 (clean air) or 4000 ppm T...

BASIS PURSUIT BASED GENETIC ALGORITHM FOR DAMAGE IDENTIFICATION

In damage detection the number of elements is generally more than the number of measured frequencies. Consequently, the corresponding damage detection equation is undetermined and thus has infinite solutions. Since in the damaged structures most of their elements remain healthy, the sparsest solution for the damage detection equation is mostly the actual damage. In the proposed method, the dama...

nondisjunction in man . predisposition to Possible evidence for genetic

SIR, As discussed in our paper (J Med Genet 1987;24: 52-9) and in the comments by Dr Harris, the number of cases available for obtaining risk figures is very small and inadequate. Furthermore, there is considerable variability between the results of various studies. Statistical tests may not be appropriate until a larger sample size is available. Although the statistical analysis does not show ...